L-5-Methyltetrahydrofolate Kaalshiyam L-5-MTHF -CAS 151533-22-1

Kaalshiyam L-5-Methyltetrahydrofolatewaa qaabka cusbada kaalshiyamka ee L-5-Methyltetrahydrofolate (L-Methylfolate), kaas oo ah qaabka ugu firfircoon uguna firfircoon ee folic acid (vitamin B9) ee jirka bini'aadamku dhab ahaantii isticmaali karo. Qaababka L- iyo 6(S)- waa kuwo firfircoon bayooloji ahaan, halka D- iyo 6(R)- aysan firfircoonayn.
Waxaa loo baahan yahay si loo sameeyo unugyo caafimaad qaba, gaar ahaan unugyada dhiigga cas. Kaabayaasha folic acid waxay ku imaan karaan qaabab kala duwan (sida L-methylfolate, levomefolate, methyltetrahydrofolate). Waxaa loo isticmaalaa in lagu daaweeyo ama looga hortago heerarka folate ee hooseeya. Heerarka folate ee hooseeya waxay keeni karaan noocyo gaar ah oo dhiig-yaraan ah.
Waa qaabka ugu firfircoon uguna shaqeynaya bayooloji ahaan ee folic acid waana mid si fudud loo nuugo marka loo eego folic acid-ka caadiga ah. Yaraanta folic acid waxay yareysaa awoodda unugyada ay u leeyihiin inay sameeyaan oo ay hagaajiyaan DNA-da, kaabistana waxay noqon kartaa hab faa'iido badan leh oo lagu kordhiyo folic acid Yaree heerarka homocysteine ​​​​iyo taageeridda koritaanka unugyada caadiga ah, shaqada endothelial-ka xididdada dhiigga, cudurrada wadnaha iyo xididdada dhiigga, iyo shaqada neerfaha, gaar ahaan xilliga uurka. Yaraanta folic acid badanaa waxay sabab u tahay yaraanta fitamiin taasoo keenta nuugid aan ku filnayn inta lagu jiro uurka iyo naasnuujinta, baahida sii kordheysa ee folic acid inta lagu jiro koritaanka ilmaha, iyo baahida loo qabo kaabista marka nuugista ama isbeddellada dheef-shiid kiimikaadka ama daawooyinka ay saameeyaan isticmaalka cuntooyinka hodanka ku ah folic acid ee aan dammaanad qaadin qiyaasta la bixiyay.