Alpha-Hydroxy-Isocaproic Acid (HICA)

HICA waa mid ka mid ah dhowr, dabiici ah, bioactive, xeryahooda organic laga helo jirka, in marka la siiyo kabitaan, si weyn u wanaajisaa waxqabadka aadanaha --creatine waa tusaale kale sida.
HICA waa erey-gaabeedka alfa-hydroxy-isocaproic acid. Waxa kale oo loo yaqaan leucic acid ama DL-2-hydroxy-4-methylvaleric acid. Marka la iska dhigo nerd-speak, HICA waa erey aad uga fudud in la xasuusto, run ahaantiina waa mid ka mid ah 5-ta maaddooyinka muhiimka ah ee ku jira badeecada MPO (Muscle Performance Optimizer).
Hadda, tani waxay u ekaan kartaa wax yar oo tangent ah laakiin igu dheji hal daqiiqo. Amino acid leucine waxa ay kicisaa mTOR waxayna muhiim u tahay kicinta isku xidhka borotiinka muruqa, kaas oo fure u ah dhisidda murqaha ama ka hortagga burburka muruqa. Waxaa laga yaabaa inaad hore u maqashay leucine sababtoo ah waa BCAA (amino acid silsilad laamo ah) iyo EAA (amino acid lagama maarmaanka u ah).
Jidhkaagu wuxuu si dabiici ah u soo saaraa HICA inta lagu jiro dheef-shiid kiimikaadka leucine. Muruqyada iyo unugyada isku xidha ayaa isticmaala oo metabolize leucine iyada oo loo marayo mid ka mid ah labada dariiqo ee biochemical ee kala duwan.
Waddada koowaad, waddada KIC, waxay qaadataa leucine waxayna abuurtaa KIC, dhexdhexaad ah, oo hadhow loo beddelo HICA. Waddada kale waxay qaadataa leucine la heli karo waxayna abuurtaa HMB (β-Hydroxy β-methylbutyric acid). Sidaa darteed, saynisyahannadu, waxay ugu yeeraan HICA, iyo ina-adeerkeed oo si fiican loo yaqaan HMB, dheef-shiid kiimikaadka leucine.
Saynis yahanadu waxay tixgeliyaan HICA inay tahay anabolic, taasoo la micno ah inay kor u qaadayso isku-dhafka borotiinka muruqa. Waxaa laga yaabaa inay tan ku sameyso siyaabo kala duwan, laakiin daraasaduhu waxay muujinayaan in HICA ay tahay anabolic sababtoo ah waxay taageertaa firfircoonida mTOR.
HICA ayaa sidoo kale lagu beeray si ay u leedahay sifooyinka anti-catabolic sidoo kale, taasoo la micno ah in ay ka caawiso ka hortagga burburka borotiinada muruqa ee laga helo unugyada muruqa gudahood.
Markaad si xoog leh u jimicsato, muruqyadaadu waxay soo maraan jug-yar oo sababa in unugyada muruqa ay burburaan. Dhammaanteen waxaan dareemeynaa saameynta jug-yar-yar 24-48 saacadood ka dib jimicsi xooggan oo ah qaabka daahitaanka muruqa xanuunka (DOMS). HICA waxay si weyn u yaraynaysaa burburkan ama catabolism. Natiijada tani waa DOMS yar, iyo muruq caato ah oo lagu dhiso.
Sidaa darteed, kabitaan ahaan, daraasaduhu waxay muujinayaan HICA waa ergogenic. Qof kasta oo raadinaya inuu kor u qaado waxqabadkiisa ciyaaraha fudud, waa inay isticmaalayaan kaabsyo uu saynisku caddeeyo inuu yahay ergogenic.